U.S. Highways by BurgerM

Chicago's Lake Shore Drive and Atlanta's Metropolitan Parkway are two of the roads that carry this route that runs from Miami to the U.P. of Michigan.

The "Grand Army of the Republic Highway", this route runs from Provincentown, Mass. to Bishop, Calif, making it the largest non-Interstate road in the United States.

Steve Earle once dubbed this Jacksonville, Florida to Mackinac City, Michigan route the "Hillbilly Highway" in song, as it was a common route for Appalachian residents looking for jobs in Ohio and Michigan.

This auxiliary route between Monticello, UT and Gallup, NM is now known as US-491, but used to be marked as what other three digit route whose two-digit parent was decommissioned in the 1980s.

Once stretching to the Bay Area, this route that includes parts of both the National Road and the Oregon Trail goes from Silver Summit, Utah to Atlantic City.

The Dire Straits song Telegraph Road refers to this U.S. highway, which one can see all of the signs saying "Sorry, We're Closed" all the way from Pontiac, Michigan to Minturn, Colorado. (Pointless host note: I met Ross Perot in Minturn)

The Trans-Canada highway serves as an unofficial connection between the two distinct segments of this northern single-digit route that has a break between St. Ignace, Michigan and Rouses Point, New York.

This route, which breaks the two-digit rule for major routes, is the major freeway connection between Los Angeles and San Francisco.

Known as the William Penn Highway through Pennsylvania, this route can take you from Cincinnati to Newark for reasons unknown.

You can revisit this route made famous in several songs starting in Wyoming, Minnesota (144 miles south of Hibbing) all the way down to New Orleans.

Likely to be supplanted by the construction of I-11 over the next 20 years, for now this route is the major route from Las Vegas to Phoenix.

Once routed from Detroit to Seattle, this route between Michigan and Minnesota has the SS Badger -- a ferry between Ludington, Michigan and Manitowoc, WI -- as part of its official route.